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. 2020 Aug 21;15(8):e0238160. doi: 10.1371/journal.pone.0238160

Table 1. General characteristics of the included studies.

First Author Publication* date (dd-mm) Continent Country Study design Sample size Quality score Mean age, years Female % Outcome Ref.
Zhu Z 22-April Ningbo China Retrospective case study 127 9 50.9 (15.3) 64.6% Severity [70]
Liu X 20-April Wuhan China Retrospective case study 124 8 56 (12) 57.1% Severity [40]
Chen X 18-April Wuhan China Retrospective case study 48 9 64.6 (18.1) 22.9% Severity [26]
Chen G 13-April Wuhan China Retrospective case study 21 8 57 (11.1) 19% Severity [24]
He R 12-April Wuhan China Retrospective case study 204 9 48.3 (20.7) 61.3% Severity [34]
Zhang G 09-April Wuhan China Retrospective case study 221 9 53.5 (20.4) 51.1% Severity [63]
Lei S 04-April Wuhan China Retrospective case study 34 9 53.7 (14.8) 58.8% ICU [36]
Wang L 30-March Wuhan China Retrospective case study 339 8 69 (7.4) 51% Mortality [53]
Guo T 27-March Wuhan China Retrospective case study 187 8 58.5 (14.7) 51.3% NA [33]
Zheng C 27-March Wuhan China Retrospective case study 55 7 57.2 (65.3) 43.6% Severity [66]
Chen T 26-March Wuhan China Retrospective case study 274 9 58.7 (19.2) 37.6% Mortality [9]
Tang X 26-March Wuhan China Retrospective case study 73 6 65.3 (11.1) 38.4% NA [49]
Shi S 25-March Wuhan China Retrospective case study 416 9 60 (54.8) 50.7% NA [48]
TO K 23-March Hong Kong China Observational cohort study 23 9 57.7 (27.5) 43.5% Severity [50]
Zhou Z 24-March Chongqing China Retrospective case study 62 9 47.2 (13.4) 45.2% Severity [69]
Chen Z 24-March Zhejiang China Retrospective case study 98 6 43 (17.2) 53.1% NA [27]
Wan S 21-March Chongqing China Retrospective case study 135 9 46 (14.1) 46.7% Severity [51]
Cheng Y 20-March Wuhan China Prospective cohort study 701 9 61.3 (15.5) 47.6% NA [28]
Luo S 20-March Wuhan China Retrospective case study 183 5 53.8 (NA) 44% NA [42]
Deng Y 20-March Wuhan China Retrospective case study 225 8 55.4 (11.5) 44.9% Mortality [30]
Arentz M 19-March Washington USA Retrospective case study 21 5 68.3 (36.3) 48% NA [21]
Chen J 19-March Shanghai China Retrospective case study 249 5 50.3 (20.7) 49.4% NA [25]
Cai Q 18-March Shenzhen China Retrospective case study 80 9 47.9 (18.7) 56.2% NA [22]
Gao Y 17-March Anhui China Retrospective case study 43 9 43.7 (11.8) 39.5% Severity [32]
Qian G 17-March Zhejiang China Retrospective case study 91 5 47.8 (15.2) 59.3% Severity [45]
Mo P 16-March Wuhan China Retrospective case study 155 8 54 (17.8) 44.5% NA [43]
Wang Z 16-March Wuhan China Retrospective case study 69 7 46.3 (20) 54% NA [54]
Lo I 15-March Macau China Retrospective case study 10 8 48.3 (27.4) 70% Severity [41]
Cheng Z 14-March Shanghai China Retrospective case study 11 5 50.4 (15.5) 27.3% NA [29]
Hsih W 13-March Taichung Taiwan Retrospective case study 2 5 45 (8.9) 50% NA [35]
Wu C 13-March Wuhan China Retrospective case study 201 8 51.3 (12.6) 36.3% Mortality [55]
Qin C 12-March Wuhan China Retrospective case study 452 9 57.3 (14.8) 48% Severity [46]
Zhao D 12-March Wuhan China Case-control study 19 7 43.7 (21.5) 42.1% NA [65]
Liu K 11-March Hainan China Retrospective case study 18 7 67.6 (3.3) 33.3% NA [38]
Zhou F 09-March Wuhan China Retrospective case study 191 9 56.3 (15.5) 38% Mortality [67]
Xiong Y 07-March Wuhan China Retrospective case study 42 5 49.5 (14.1) 40% NA [58]
Fan B 04-March Singapore Singapore Retrospective case study 67 9 43.7 (14.1) 44.8% ICU [31]
Young B 03-March Sengkang Singapore Descriptive case series 18 7 50.3 (31.1) 50% NA [62]
Wu J 29-February Jiangsu China Retrospective case study 80 7 46.1 (15.4) 51.2% NA [56]
Li K 29-February Chongqing China Retrospective case study 83 9 45.5 (12.3) 47% Severity [37]
Liu W 28-February Wuhan China Retrospective case study 78 9 42.7 (17.8) 50% NA [39]
Yang W 26-February Zhejiang China Retrospective case study 149 6 45.1 (13.3) 45.6% NA [60]
Wu J 25-February Chongqing China Retrospective case study 80 6 44 (11) 48% NA [57]
Shi H 24-February Wuhan China Retrospective case study 81 7 49.5 (11) 48% NA [47]
Yang X 24-February Wuhan China Retrospective case study 52 9 59.7 (13.3) 33% Mortality [61]
Zhang J 23-February Wuhan China Retrospective case study 138 9 56.3 (45.9) 49.3% Severity [64]
Zhou W 21-February Wuhan China Retrospective case study 15 8 61.7 (9.6) 33.3% Mortality [68]
Xu X 19-February Zhejiang China Retrospective case study 62 7 41.7 (14.8) 44% NA [59]
Pan F 13-February Wuhan China Retrospective case study 21 6 40 (9) 74% NA [44]
Chang D 07-February Beijing China Retrospective case study 13 6 38.7 (10.4) 23.1% NA [23]
Wang D 07-February Wuhan China Retrospective case study 138 9 55.3 (19.2) 45.7% ICU [52]
Huang C 24-January Wuhan China Prospective cohort study 41 9 49.3 (12.6) 27% ICU [1]

*All articles were published in 2020.

NA: not applicable.