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. Author manuscript; available in PMC: 2020 Aug 25.
Published in final edited form as: Cancer Res. 2018 Jan 4;78(5):1266–1274. doi: 10.1158/0008-5472.CAN-17-1718

Figure 3.

Figure 3.

Histologic analysis of Vhl-mutant mice reveals PFV. A and B, Funduscopic and histologic images of a 5-month-old control mouse. The hyaloid artery has completely regressed. C and D, Representative funduscopy and histologic images of a 5-month-old Vhl-mutant mouse. Black arrow, persistent hyaloid vessel; red arrow, retinal neovascularization in the vitreous. E–G, Another Vhl-mutant mouse of similar age exhibited persistent hyaloid vessel (F, arrow), and vitreous fibro-neovascular structure adherent to the lens (G, arrow). Scale bars for B, D, F, G, 100 μm.