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. 2020 Aug 25;15(8):e0238207. doi: 10.1371/journal.pone.0238207

Table 3. Clinical course of UM in DTC patients (n = 19).

Diagnostic method for UM
 Pathology 10 (52.6)
 FNA 4 (21.1)
 Biopsy 5 (31.3)
 Surgical specimen 1 (6.3)
 Imaging studies 9 (47.4)
 RAI uptake ± CT/MRI 2 (10.5)
 18-FDG uptake ± CT/MRI 7 (36.8)
First-line therapy for UM
 Observation 4 (21.1)
 Local treatment 5 (31.3)
 Surgery (including excision) 3 (15.8)
 RFA 2 (10.5)
 Systemic treatment 10 (52.6)
  TKI therapy 5 (31.3)
  RAI ablation therapy 4 (21.1)
  Systemic chemotherapy 1 (5.3)
Mortality rate 6 (31.6)
 Cancer-related mortality 6 (31.6)
 Treatment-related mortality 0 (0.0)
Median follow-up months from UM diagnosis (IQR) 20.0 (11.0–55.0)

UM: unusual metastasis; RAI: radioactive iodine; FDG: fluoro-deoxy-glucose; RFA: radiofrequency ablation; TKI: tyrosine kinase inhibitor; IQR: interquartile range