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. 2020 Aug 25;15(8):e0237603. doi: 10.1371/journal.pone.0237603

Table 1. Species-specific prespecified threshold criteria (adapted from Leibowitz).

Group [Threshold criteria] Species
I [1 CFU/mL]

  • Streptococcus pyogenes

  • Streptococcus pneumoniae

  • Gram-negative spp. (except Moraxella catarrhalis)
II [10 CFU/mL]

  • Staphylococcus aureus

  • Streptococcus spp. (except S. pyogenes and S. pneumoniae)

  • Moraxella catarrhalis
III [100 CFU/mL]

  • Staphylococcus spp. (except S. aureus)

  • Micrococcus spp.

  • Bacillus spp.
IV [1000 CFU/mL]

  • Corynebacterium spp.