Table 3. Subject demographics and baseline pathogens in poly- and monobacterial conjunctivitis infections.
| All culture-confirmed subjects (N = 1,041) | |||||
|---|---|---|---|---|---|
| Polybacterial Infections (n = 177) | Monobacterial Infections (n = 864) | P-value | |||
| Age, years | |||||
| mean (SD) | 32.9 | (28.9) | 29.7 | (25.3) | 0.330a |
| Min, max | 1, | 98 | 0, | 100 | |
| Gender, female n (%) | 100 | (56.5) | 488 | (56.5) | 0.862b |
| Viral coinfection, n (%)c | 14 | (7.9) | 14 | (1.6) | <0.001b |
| Dominant infecting species, n (%) | |||||
| H. influenzae | 45 | (25.4) | 288 | (33.3) | 0.042d |
| S. aureus | 26 | (14.7) | 110 | (12.7) | 0.465d |
| S. pneumoniae | 22 | (12.4) | 272 | (31.5) | <0.001d |
| encapsulated | 6 | (3.4) | 13 | (1.5) | |
| S. mitis/S. mitis group | 14 | (7.9) | 21 | (2.4) | <0.001d |
| S. epidermidis | 6 | (3.4) | 54 | (6.2) | 0.158d |
| S. maltophilia | 6 | (3.4) | 2 | (0.2) | <0.001d |
| S. oralis | 5 | (2.8) | 3 | (0.3) | 0.005d |
aANOVA with fixed effects of infection type and clinical study
bCMH tests stratified by clinical study.
cTwelve subjects in each group were infected with adenovirus and two with herpes simplex virus.
dFisher’s exact tests.
Only those species identified as dominant ≥ 5 times among polybacterial infections are shown.