Table 1. Descriptive statistics for the overall cohort and the infectious uveitis/scleritis sample.
| Total Optum | Any Infectious Uveitis/Scleritis | p-value | |||
|---|---|---|---|---|---|
| Sample Size, n | 21,504,368 | 18,523 | |||
| Mean age, years (sd) | 40.5 | (22.7) | 57.6 | (17.6) | <0.01 |
| Male, n (%) | 10,486,782 | (48.77%) | 7,580 | (40.92%) | <0.01 |
| Race, n (%) | |||||
| Non-Hispanic white | 13,601,491 | (63.25%) | 13,007 | (70.22%) | <0.01 |
| Black | 1,874,353 | (8.72%) | 1,712 | (9.24%) | 0.01 |
| Hispanic | 2,267,992 | (10.55%) | 1,027 | (5.54%) | <0.01 |
| Asian | 988,291 | (4.60%) | 397 | (2.14%) | <0.01 |
| Unknown or missing | 2,772,241 | (12.89%) | 2,380 | (12.85%) | 0.86 |
| Education, n (%) | |||||
| Less than high school | 133,013 | (0.62%) | 53 | (0.29%) | <0.01 |
| High school only | 5,278,876 | (24.55%) | 4,955 | (26.75%) | <0.01 |
| Some college | 11,288,872 | (52.50%) | 9,769 | (52.74%) | 0.51 |
| 4 year college degree or better | 4,320,623 | (20.09%) | 3,418 | (18.45%) | <0.01 |
| Unknown or missing | 482,984 | (2.25%) | 328 | (1.77%) | <0.01 |
| Income, n (%) | |||||
| $40K-$49k | 4,054,808 | (18.86%) | 4,650 | (25.10%) | <0.01 |
| $50K-$99k | 5,541,428 | (25.77%) | 5,590 | (30.18%) | <0.01 |
| $100k+ | 6,660,998 | (30.98%) | 5,323 | (28.74%) | <0.01 |
| Unknown or missing | 5,247,134 | (24.40%) | 2,960 | (15.98%) | <0.01 |
| Census Division, n (%) | |||||
| East North Central | 3,045,565 | (14.16%) | 3,741 | (20.20%) | <0.01 |
| East South Central | 762,789 | (3.55%) | 1,177 | (6.35%) | <0.01 |
| Middle Atlantic | 1,449,644 | (6.74%) | 1,095 | (5.91%) | <0.01 |
| Mountain | 2,004,201 | (9.32%) | 1,236 | (6.67%) | <0.01 |
| New England | 729,613 | (3.39%) | 648 | (3.50%) | 0.43 |
| Pacific | 2,933,513 | (13.64%) | 1,207 | (6.52%) | <0.01 |
| South Atlantic | 5,157,140 | (23.98%) | 4,832 | (26.09%) | <0.01 |
| West North Central | 164,916 | (0.77%) | 30 | (0.16%) | <0.01 |
| West South Central | 2,186,591 | (10.17%) | 2,427 | (13.10%) | <0.01 |
| Unknown | 3,070,396 | (14.28%) | 2,130 | (11.50%) | <0.01 |
| Smoking, n (%) | 312,107 | (1.45%) | 590 | (3.19%) | <0.01 |
| Comorbidities | |||||
| Congestive Heart Failure | 227,486 | (1.06%) | 550 | (2.97%) | <0.01 |
| Cardiac Arrhythmia | 503,879 | (2.34%) | 1,212 | (6.54%) | <0.01 |
| Valvular Disease | 216,972 | (1.01%) | 552 | (2.98%) | <0.01 |
| Peripheral Vascular Disorders | 263,317 | (1.22%) | 592 | (3.20%) | <0.01 |
| Hypertension | 2,571,554 | (11.96%) | 5,484 | (29.61%) | <0.01 |
| Other Neurological Disorders | 185,502 | (0.86%) | 381 | (2.06%) | <0.01 |
| Chronic Pulmonary Disease | 809,582 | (3.76%) | 1,555 | (8.39%) | <0.01 |
| Diabetes | 1,230,172 | (5.72%) | 2,813 | (15.19%) | <0.01 |
| Hypothyroidism | 697,083 | (3.24%) | 1,378 | (7.44%) | <0.01 |
| Renal Failure | 260,077 | (1.21%) | 682 | (3.68%) | <0.01 |
| Liver Disease | 133,699 | (0.62%) | 278 | (1.50%) | <0.01 |
| Peptic Ulcer Disease | 22,584 | (0.11%) | 54 | (0.29%) | <0.01 |
| AIDS/HIV | 21,916 | (0.10%) | 107 | (0.58%) | <0.01 |
| Cancer | 360,781 | (1.68%) | 853 | (4.61%) | <0.01 |
| Rheumatologic disease | 211,962 | (0.99%) | 632 | (3.41%) | <0.01 |
| Obesity | 332,758 | (1.55%) | 566 | (3.06%) | <0.01 |
| Weight Loss | 88,064 | (0.41%) | 235 | (1.27%) | <0.01 |
| Fluid and Electrolyte Disorders | 212,795 | (0.99%) | 597 | (3.22%) | <0.01 |
| Anemia | 193,727 | (0.90%) | 456 | (2.46%) | <0.01 |
| Substance Abuse | 107,231 | (0.50%) | 137 | (0.74%) | <0.01 |
| Psychoses | 60,462 | (0.28%) | 118 | (0.64%) | <0.01 |
| Depression | 763,452 | (3.55%) | 1,104 | (5.96%) | <0.01 |
| Other | 152,296 | (0.71%) | 397 | (2.14%) | <0.01 |
EPO = exclusive provider organization; HMO = health maintenance organization; IND = indemnity; OTH = other; POS = point of service; PPO = preferred provider organization; AIDS = acquired immunodeficiency syndrome; HIV = human immunodeficiency virus
Data for total Optum population is shaded in gray, data for any infectious uveitis/scleritis is shaded in purple.