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. Author manuscript; available in PMC: 2020 Aug 25.
Published in final edited form as: BJU Int. 2010 Aug 27;107(3):416–424. doi: 10.1111/j.1464-410X.2010.09569.x

FIG. 1.

FIG. 1.

Microvascular density in primary kidney tumours. A, B, Representative patterns of capillary blood vessels shown by staining for the pan-endothelial marker CD31. Well-organized glomerulal structures in cortical sections of the normal kidney A, contrast with chaotic blood vessels in RCC B,. C. Hot spot MVD of benign (oncocytoma) and malignant (RCC) kidney tumours. Notably, MVD in oncocytoma resembles that of normal kidney cortex (NK, dotted line), while an extremely wide MVD distribution is observed in RCC. D, Separation of the RCC cohort into RCC sub-sets shows higher MVD in ccRCC, than in non-ccRCC (nccRCC) and metastatic (mRCC) tumours. The latter difference is statistically significant (P < 0.05), even though the values for individual patients continue to exhibit wide heterogeneity. Median values are denoted by thick horizontal lines.