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RAS system and targets of conventional RAS inhibitors. Ang I, angiotensin I; ACE, angiotensin-converting enzyme; Ang II, angiotensin II; Ang 1–7, angiotensin 1–7; ACEi, ACE inhibitors; MRAs, mineralocorticoid receptor agonists; ARBs, angiotensin II receptor blockers; AT1, Ang II type I receptors
