Table 5.

Logistic Regression Model for C4B Load in Severe cCSC Patients

Overall Significance Model P = 0.007
	Controls (n = 250)	Severe cCSC (n = 164)	P	OR (95% CI)
Male sex	198 (79%)	143 (87%)	0.010	0.48 (0.27–0.84)
C4B copy number
0	6 (2.4%)	4 (2%)	0.781	0.83 (0.23–3.04)
1	55 (22%)	51 (31%)	0.225	1.33 (0.84–2.12)
2	142 (57%)	99 (60%)	Base	Base
3	44 (18%)	10 (6%)	0.001*	0.29 (0.14–0.61)
4	3 (1.2%)	0	0.999	NA

^*P-values < 0.0055 were considered significant after correction for multiple testing.

C4B, complement component 4; NA, not annotated.