Figure 3.

Aortic injury together with hyperlipidemia promotes plaque progression in the aortic root and aortic arch. A, Quantification of plaque burden in the aortic root and (B) aortic arch as measured by the late gadolinium enhancement (LGE)-magnetic resonance imaging (MRI) images (n=6–7/group). C, Representative trichrome staining of plaques located in the aortic arch from the different experimental groups. Data were represented as mean±SEM. For multiple-group comparisons, data were analyzed with a Kruskal-Wallis ANOVA with Dunn post hoc test. DE indicates delayed enhancement; and HFD, high-fat diet. *P<0.05 and **P<0.01.