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. 2020 Jul 16;40(9):2159–2170. doi: 10.1161/ATVBAHA.120.314387

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© 2020 The Authors.

Arteriosclerosis, Thrombosis, and Vascular Biology is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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Figure 4. — Sustained arterial inflammation triggers a persistent increase of the inflammatory cytokine interleukin IL (interleukin)-6. A, Quantification of the proinflammatory cytokine IL-6 at the acute phase and (B) 12 wk after aortic injury (n=6–9/group). C, Flow cytometric quantification of blood monocytes (n=4–6/group). D, Pie charts show the relative proportion of Ly6C^hi and Ly6C^lo monocytes in all the groups at different time points (n=4–6/group). Data were represented as mean±SEM. For multiple-group comparisons, data were analyzed with a Kruskal-Wallis ANOVA with Dunn post hoc test. HFD indicates high-fat diet; hi, high; and lo, low. *P<0.05, **P<0.01, and ***P<0.001.