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. 2020 Aug 25;95(11):2320–2324. doi: 10.1016/j.mayocp.2020.08.023

Table 2.

Key Considerations for Prevention of Gastrointestinal Tract Transmission of Human Coronaviruses in Hospitals

Recommendation Key points
1. Elevate awareness about GI symptoms of COVID-19 and potential for fecal-oral transmission
  • Around one-fifth of COVID-19 patients have GI symptoms

  • Index patient in a previous large SARS outbreak had diarrhea

  • Teach staff to recognize COVID-19 cases without respiratory symptoms

  • Post signs alerting patients and staff to all symptoms of COVID-19 (fever, respiratory, GI)

  • Ask screening questions about GI symptoms even if patients do not have fever or respiratory symptoms

2. Consider scaling up isolation precautions
  • Isolate patients with n/v, diarrhea, and other GI tract symptoms under the appropriate airborne and contact protocols

  • Two possible modes of transmission:
    • Contaminated surfaces (fomites)
    • Bioaerosols from flushing uncovered toilets
  • Diarrhea possibly indicates higher viral RNA positivity and viral load in stool

3. Improve environmental controls
  • Consider that toilet flushing could be an aerosol-generating procedure

  • Closing the toilet lid before flushing provides a 12-fold reduction in bioaerosol spread

  • Ensure adequate ventilation and plumbing systems

COVID-19 = novel coronavirus disease 2019; GI = gastrointestinal; n/v = nausea and vomiting.