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. 2020 Aug 25;533(3):467–473. doi: 10.1016/j.bbrc.2020.08.086

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Fig. 2 — Inhibition of 2019-nCoV M^pro activity by andrographolide and its derivatives. Protease activities of 2019-nCoV M^pro or SARS-CoV M^pro in the presence of inhibitors at five different concentrations was measured. IC₅₀ of (A) andrographolide (B) Andro-NBD (C) NCTU-048 and (D) disulfiram were determined and shown respectively. All the experiments were independently carried out in triplicates.

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