Table 2.

YHEC modelled outcomes of FIT compared with FC based on sensitivity and specificity per thousand patients using McDonald et al, Godber et al and Mowat et al as the comparators

Faecal biomarker	Total costs	Correctly diagnosed non-OED	Correctly diagnosed OED	Unnecessary colonoscopies	Clinician attendance	Incremental costs
FIT≥10 µg/g comparator: McDonald et al*	£258 179	931	32	9	139	−£70 908
FIT≥10 µg/g comparator: Godber et al*	£360 117	752	43	188	304	£30 938
FIT≥10 µg/g comparator: Mowat et al*	£338 517	790	41	150	270	£9338
FC ≥100 µg/g	£329 179	812	49	125	270	Referent

FC, faecal calprotectin; FIT, faecal immunochemical test for haemoglobin; OED, organic enteric disease, a composite of colorectal cancer, significant adenomatous polyps and inflammatory bowel disease.