Table 3.

Local investigations and key information to include in referral letter (more details in online supplementary appendices 3–5)

Comorbidity (include all details of pathologies, and important negatives)	Investigations (general investigations as below)	Disease-specific investigations
Cardiovascular	Chest X-ray	PSC: colonoscopy and recent liver imaging
Respiratory	ECG	PBC/AIH: drug history
Renal	Echocardiogram	Hepatitis B: screening tests and viral load
Bone	Oxygen Saturation	Hepatitis C: details of treatment
HIV	Analysis of Ascites	HCC: recent imaging and MDT discussions
Obesity	Endoscopy	PLD/PLKD: brain imaging for Berry aneurysms
Surgical/anaesthetic history	Nutritional assessment	Budd-Chiari syndrome: history of shunts.
Nutrition	Assessment of the performance status	Wilson’s disease: details of treatments
Metabolic syndrome	Up to date blood tests and UKELD	Encephalopathy: brain imaging, ammonia, number connection tests
Non-hepatic cancer	Adherence/addiction
Infectious disease		Ascites: number of drains, episodes of SBP
Social support		Alcohol related liver disease: period of abstinence, engagement with addiction services and so on
Disabilities
Alcohol and substance abuse
Mental health
Smoking

AIH, Autoimmune Hepatitis; ArLD, Alcohol related Liver Disease; HCC, Hepatocellular Carcinoma; MDT, Multi Disciplinary Team; NG, Naso-gastric; NICE, National Institute for Health & Care Excellence; PBC, Primary Biliary Cholangitis; PLD/PLKD, Polycystic Liver Disease/Polycystic Liver & Kidney Disease; PSC, Primary Sclerosing Cholangitis; SBP, Spontaneous Bacterial Peritonitis; TC, Transplant Co-ordinator.