Table 4.

Absolute and relative contra-indications to LT

Absolute contraindications	Relative contraindications*
Untreated HIV*	Inadequate social support
Severe extrahepatic disease with predicted mortality >50% at 5 years including psychiatric disorder	Smoking
Severe irreversible pulmonary disease	Certain anatomical variants
Ongoing alcohol misuse	Extensive previous abdominal surgery
Active illicit drug use	BMI >40 kg/m2
Certain anatomic variants	Poor clinic attendance and/or adherence
Ongoing extra-hepatic sepsis*
Active or previous extra-hepatic malignancy†
Liver cancer outside criteria*

*These contra-indications can be temporary and require discussion with LTU.

†LT is considered for patients with neuroendocrine tumours (requires referral to national panel).⁴⁶

BMI, body mass index; LT, liver transplant; LTU, liver transplant unit.