Table I.
Upregulated genes by overexpression of NRP1 using RNA-Seq.
| No. | Symbol | Description | FPKM
|
P-value | |
|---|---|---|---|---|---|
| Control | NRP1 | ||||
| 1 | MAPK7 | Mitogen-activated protein kinase 7 | 0.001 | 0.543 | 2.718×10−06 |
| 2 | CDC42BPA | CDC42 binding protein kinase α | 0.001 | 0.267 | 5.426×10−05 |
| 3 | CAMKK2 | Calcium/calmodulin-dependent protein kinase kinase 2 | 0.001 | 0.687 | 1.347×10−05 |
| 4 | APLP2 | Amyloid β precursor like protein 2 | 0.230 | 11.753 | 1.687×10−08 |
| 5 | RHOT1 | Ras homolog family member T1 | 0.001 | 1.370 | 1.032×10−11 |
| 6 | NRDC | Nardilysin convertase | 0.001 | 1.950 | 3.621×10−07 |
| 7 | TPM1 | Tropomyosin 1 | 0.001 | 0.900 | 5.959×10−06 |
| 8 | CASP10 | Caspase-10 | 0.001 | 0.263 | 1.351×10−06 |
| 9 | PCMTD1 | Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | 0.001 | 1.280 | 2.477×10−06 |
| 10 | RRBP1 | Ribosome binding protein 1 | 0.001 | 0.727 | 5.203×10−05 |
| 11 | HIVEP2 | Human immunodeficiency virus type I enhancer-binding protein 2 | 1.813 | 0.837 | 6.189×10−05 |
| 12 | PTPRK | Protein tyrosine phosphatase, receptor type K | 0.001 | 0.383 | 5.873×10−07 |
| 13 | ZNF462 | Zinc finger protein 462 | 0.001 | 0.417 | 6.091×10−08 |
| 14 | NRP1 | Neuropilin 1 | 0.930 | 960.273 | 2.646×10−18 |
| 15 | ABCF1 | ATP binding cassette subfamily F member 1 | 0.003 | 1.083 | 1.727×10−11 |
| 16 | NSD2 | Nuclear receptor binding SET domain protein 2 | 0.001 | 0.253 | 8.008×10−07 |
| 17 | MGAT1 | Mannosyl (α-1,3-)-glycoprotein β-1,2-N-acetylglucosaminyltransferase | 0.001 | 1.430 | 1.994×10−11 |
| 18 | LRRC37A | Leucine rich repeat containing 37A | 0.001 | 0.253 | 1.017×10−05 |
| 19 | ELP5 | Elongator acetyltransferase complex subunit 5 | 0.001 | 1.007 | 2.366×10−05 |
| 20 | NEB | Nebulin | 0.001 | 0.053 | 4.932×10−06 |
| 21 | DIAPH3 | Diaphanous related formin 3 | 0.001 | 0.777 | 1.002×10−07 |
| 22 | SEMA4D | Semaphorin 4D | 0.001 | 1.027 | 1.650×10−13 |
| 23 | ZNF566 | Zinc finger protein 566 | 0.007 | 0.490 | 5.861×10−05 |
| 24 | VRK2 | Vaccinia related kinase 2 | 0.001 | 1.510 | 8.116×10−05 |
| 25 | LANCL1 | LanC like 1 | 0.001 | 0.570 | 7.683×10−05 |
| 26 | 8 Sep | Septin 8 | 0.001 | 1.700 | 1.013×10−06 |
| 27 | OSBPL9 | Oxysterol binding protein like 9 | 0.001 | 0.507 | 3.895×10−06 |
| 28 | TACC3 | Transforming acidic coiled-coil protein 3 | 0.001 | 2.230 | 4.007×10−07 |
| 29 | SLBP | Stem-loop binding protein | 1.940 | 0.040 | 2.892×10−05 |
| 30 | HNRNPH1 | Heterogeneous nuclear ribonucleoprotein H1 | 0.001 | 6.140 | 1.272×10−12 |
| 31 | ASPH | Aspartate β-hydroxylase | 0.113 | 2.607 | 6.574×10−05 |
| 32 | DNPEP | Aspartyl aminopeptidase | 0.001 | 3.310 | 2.407×10−06 |
| 33 | ATP2C1 | ATPase secretory pathway Ca2+ transporting 1 | 0.843 | 2.737 | 1.329×10−05 |
| 34 | SLC38A2 | Solute carrier family 38 member 2 | 2.913 | 7.513 | 1.511×10−05 |
| 35 | HSP90AA1 | Heat shock protein 90 α family class A member 1 | 19.937 | 5.660 | 8.247×10−05 |
| 36 | C16orf58 | Chromosome 16 open reading frame 58 | 0.007 | 1.153 | 4.260×10−07 |
| 37 | NCOA4 | Nuclear receptor coactivator 4 | 0.001 | 1.097 | 3.774×10−08 |
| 38 | RPL17-C18orf32 | RPL17-C18orf32 readthrough | 0.001 | 2.440 | 7.856×10−12 |
| 39 | NCOA4 | Nuclear receptor coactivator 4 | 0.001 | 0.847 | 1.586×10−06 |
| 40 | FCHO1 | FCH domain only 1 | 0.001 | 0.913 | 8.297×10−10 |
| 41 | PRKD2 | Protein kinase D2 | 0.001 | 1.423 | 7.957×10−06 |
| 42 | GAS2L1 | Growth arrest specific 2 like 1 | 0.001 | 3.313 | 4.079×10−07 |
| 43 | RPH3AL | Rabphilin 3A like (without C2 domains) | 0.010 | 0.550 | 5.177×10−05 |
| 44 | MAPKAPK3 | Mitogen-activated protein kinase-activated protein kinase 3 | 0.003 | 0.960 | 8.374×10−06 |
| 45 | TCF7L2 | Transcription factor 7 like 2 | 0.001 | 0.363 | 1.569×10−05 |
| 46 | EAW79261 | hCG2022618 [Homo sapiens] | 0.001 | 0.293 | 5.914×10−05 |