Figure 1.

BANCR and IGF1R are upregulated in human ESCC tissues. (A and B) RT-qPCR was applied to examine the expression levels of (A) BANCR and (B) IGF1R in ESCC tissues and adjacent normal tissues. (C) The correlation between BANCR and IGF1R was determined by Spearman's correlation analysis. (D) The levels of IGF1R protein were detected by western blot analysis. (E) The overall survival of ESCC patients with high or low BANCR expression was determined by Kaplan-Meier analysis followed by the log-rank test. Data are presented as the means ± standard error of 3 experimental results. The Student's t-test was applied to compare differences between groups. ^*P<0.05. BANCR, BRAF activated non-coding RNA; ESCC, esophageal squamous cell carcinoma.