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Effect of AC on the expression of genes associated with the cell cycle. (A) mRNA levels of CDK4, Cyclin D1, P53 and P21 in HCT116 cells treated with AC for 72 h. (B) Representative western blots of CDK4, Cyclin D1, P53 and P21 in HCT116 cells treated with AC for 72 h; and (C) quantification. Data are expressed as mean ± standard deviation from three independent experiments. *P<0.05 vs. control cells. AC, asiaticoside.
