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. 2020 Aug 6;143(8):2502–2518. doi: 10.1093/brain/awaa198

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© The Author(s) (2020). Published by Oxford University Press on behalf of the Guarantors of Brain.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Pupil reward sensitivity in those who developed a QUIP score > 0. PD-no-ICD group split based on QUIP-anytime scores collected 4–5 years after behavioural testing with the eye tracking paradigm. (A) Mean pupillary reward sensitivity ON dopamine significantly greater in PD-no-ICD with QUIP > 0 compared to PD-no-ICD with QUIP = 0. (B) Mean overall pupillary reward sensitivity (ON and OFF dopamine combined) significantly greater in PD-no-ICD with QUIP > 0 compared to PD-no-ICD with QUIP = 0. The line within the box indicates the median; the ‘x’ within depicts the mean.