Table 3.
Correlation between marker expression and cell viability post-HER2 pathway-targeted drug treatment in trastuzumab-resistant cell models.
| Cell model | Marker | Correlation coefficienta | p Value |
|---|---|---|---|
| pERK1/2 | 0.13 | 0.73 | |
| pAkt | 0.17 | 0.67 | |
| BT474R | p-rpS6 | 0.78 | 0.013 |
| pS6K1 | 0.73 | 0.025 | |
| p-mTOR | 0.60 | 0.088 | |
| pHER2 | 0.067 | 0.86 | |
| p4EBP1 | 0.20 | 0.61 | |
| pERK1/2 | −0.05 | 0.9 | |
| pAkt | 0.35 | 0.36 | |
| SKBR3R | p-rpS6 | 0.88 | 0.002 |
| pS6K1 | 0.64 | 0.061 | |
| p-mTOR | 0.62 | 0.077 | |
| pHER2 | <0.01 | 0.99 | |
| p4EBP1 | 0.72 | 0.030 | |
Spearman correlation coefficient.