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MiR-425-5p targets PTEN in LCa. a. Predicted binding of miR-425-5p and PTEN. b & c. Relative luciferase activity of PTEN-WT, PTEN-MUT in LCa cells expressing miR-425-5p mimic. d. PTEN mRNA levels are significantly lower after transfection with miR-425-5p mimic. e. PTEN expression assessed by WB. Full-length blots/gels are presented in Supplementary Figure 1. f. miR-425-5p and PTEN negatively correlate in LCa tissue. Data: mean ± SD. * P < 0.05; ** P < 0.01; *** P < 0.001
