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. 2020 Aug 26;39(4):321–330. doi: 10.1007/s12664-020-01069-0

Table 4.

Live vaccine schedule for inflammatory bowel disease patientsa,b

Vaccine (brand names) Target group Dosing scheduleb Comments
Mumps, measles, rubella (M-M-R) If vaccination history unknown Two doses 0.5 mL IM at least 4 weeks apart Contraindicated in patients on immunosuppression
Varicella (Zuvicella) If vaccination history unknown Two doses 0.5 mL SC at least 4 weeks apart Contraindicated in patients on immunosuppression
Herpes zoster (Zostavax) Patients age > 50 years with unknown vaccination history irrespective of previous exposure Single dose of 0.65 mL SC Patients on low-level immunosuppression may be vaccinated

IM intramuscular, SC subcutaneous

aLive vaccines should be administered in IBD patients 4–6 weeks before initiating immunosuppressive therapy

bDose of vaccine may vary. Please refer to the product monograph before administration