Fig. 9.

Tumour volume recorded for the studied animal groups every 2 days from the 1st day of the treatment to the last record at the 16th day (the end of the experiment). Values are mean ± SEM with n = 6. *p < 0.05, **p < 0.01, ***p < 0.001 compared with control group. ^Δp < 0.05, ^ΔΔp < 0.01, ^ΔΔΔp < 0.001 compared with animal treated by free SL at a dose of (10 mg kg⁻¹) (a). Percentage tumour growth inhibition (% TGI) in animals treated with free SL or SL-loaded NC (F9) at a dose of (10 mg kg⁻¹) ^Δp < 0.05, ^ΔΔp < 0.01, ^ΔΔΔp < 0.001 compared with animal treated by free SL (b). Tumour weight of studied groups after the end of the experiment. Values are mean ± SEM with n = 6. p < 0.05, **p < 0.01, ***p < 0.001 compared with control group. ^Δp < 0.05, ^ΔΔp < 0.01, ^ΔΔΔp < 0.001 compared with animals treated by free SL at a dose of (10 mg kg⁻¹) (c)