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. 2020 Aug 25;11:4078. doi: 10.1038/s41467-020-17930-x

Fig. 2. Blood replacement protects the brain from cell death in stroke mice.

Fig. 2

Microscopic images of brain tissue taken from stroke mice underwent tMCAO for 90 min followed by 22.5 h reperfusion. The blood replacement (BR) group received 500 µl of blood from healthy donors (3~6 months old) at 6.5~7 h post stroke. a The Cresyl violet staining, b H&E staining, c TUNEL staining counterstained with Methyl Green, and d Fluoro-Jade C staining were performed on paraffin embedded brain slices. Red rectangles indicate the magnified areas evaluated under ×40 magnification. Both the cortex and striatum were evaluated. Experiments were repeated five times with similar results and images were presentative of one mouse from five mice per group. Scale bars = 20 µm.