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. 2020 Jul 13;302(3):763–777. doi: 10.1007/s00404-020-05682-4
Evidence-based recommendation
Level of Evidence 2b Grade of recommendation A Degree of consensus +  + 
Women should be informed that EPT does not increase their cardiovascular risk or has only a minor effect. ET does not increase cardiovascular risk or may even reduce it. HRT is not appropriate for the primary or secondary prevention of coronary heart disease. HRT should be started before the age of 60 years for the treatment of climacteric symptoms