Table 2.
Drug release kinetics data of optimized niosomal dispersion, MB aqueous solution, and gel formulations
| Zero order | First order | Korsmeyer–Peppas | Higuchi | ||
|---|---|---|---|---|---|
| RSQ | RSQ | RSQ | n | RSQ | |
| Niosomal dispersion | 0.9577 | 0.8439 | 0.9987 | 0.5053 | 0.9973 |
| Free drug solution | 0.6892 | 0.5747 | 0.8973 | – | 0.8408 |
| Niosomal gel | 0.9452 | 0.8516 | 0.9848 | 0.4792 | 0.9811 |
| Free drug gel | 0.8928 | 0.7793 | 0.9906 | 0.474 | 0.9769 |
RSQ: linear regression coefficient; n: diffusional exponent in Korsmeyer–Peppas model; β: diffusional exponent in Weibull model