Fig. 1.

Beta diversity shows clear differences in gut microbiota composition between vendors. Fecal pellets were collected from mice from 3 different vendors (Janvier, Envigo, and Charles River) before intranasal inoculation with LPS or K. pneumoniae. a Bray-Curtis-based non-metric multidimensional scaling (NMDS) plot for all microbiome samples shows clearly separated clusters for each vendor. b Bray-Curtis NMDS heatmap in which the lines represent single amplicon sequence variants, in which a darker color correlates to a higher abundance. c Unweighted unifrac and weighted unifrac (d). The abbreviations used to indicate vendors are as follows: Janvier (Jan), Envigo (Env), and Charles River (CR), n = 8