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. 2020 Mar 20;57(10):3545–3555. doi: 10.1007/s13197-020-04360-2

Table 1.

Methods for the preparation of nanoliposome in food and nutraceutical ingredients

Preparation techniques Food and nutraceutical ingredients References
Passive loading techniques
Mechanical dispersion method
 Lipid film hydration Hemoglobin Li et al. (2005)
 Micro emulsification Nisoldipine Nekkanti et al. (2016)
 Sonication Resveratrol Isailović et al. (2013)
 Membrane extrusion Hemoglobin Li et al. (2005)
 Dried reconstituted vesicles Ketoprofen Li and Deng (2004)
Solvent dispersion method
 Ethanol or ether injection Salidroside Fang and Bhandari (2010)
 Double emulsion Flurbiprofen Liu et al. (2012)
 Reverse phase evaporation vesicles Bovine serum albumin Ko and Bickel (2012)
Detergent removal technique
 Dialysis Poly(γ-benzyl L glutamate) Marsden et al. (2010)
 Gel permeation chromatography Fisetin (3,3′,4′,7-tetrahydroxyflavone) Mignet et al. (2012)
 Diffusion Resveratrol Isailović et al. (2013)
Active loading techniques
Citrate method Doxorubicin citrate Swenson et al. (2001)
Ammonium sulfate method Brucine Chen et al. (2010)
Ionophore generated pH gradient method Ciprofloxacin Johnston et al. (2006)
EDTA ion grading method Topotecan Yang et al. (2012)