Table 2.
Odds ratios (ORs) and 95% confidence intervals (CIs) for hypertension in relation to platelets and reticulocytes among total participants.
Platelet tertiles | p for trend | 1 SD increment of platelets | |||
---|---|---|---|---|---|
T1 (low) | T2 | T3 (high) | |||
No. of participants | 441 | 432 | 440 | ||
No. of cases (%) | 244 (55.3) | 270 (62.5) | 279 (63.4) | ||
Model 1 | 1.00 | 1.47 (1.11, 1.94) | 1.61 (1.22, 2.14) | < 0.001 | 1.23 (1.10, 1.39) |
Model 2 | 1.00 | 1.38 (1.02, 1.85) | 1.56 (1.16, 2.09) | 0.004 | 1.22 (1.08, 1.38) |
Reticulocyte tertiles | P for trend | 1 SD increment of reticulocytes | |||
---|---|---|---|---|---|
T1 (low) | T2 | T3 (high) | |||
No. of participants | 437 | 438 | 438 | ||
No. of cases (%) | 239 (54.7) | 264 (60.3) | 290 (66.2) | ||
Model 1 | 1.00 | 1.31 (0.99, 1.73) | 1.88 (1.42, 2.50) | < 0.001 | 1.44 (1.26, 1.64) |
Model 2 | 1.00 | 1.09 (0.81, 1.45) | 1.21 (0.89, 1.65) | 0.222 | 1.19 (1.03, 1.36) |
Model 1: Adjusted only for sex and age. Model 2: Adjusted further for sex and age, alcohol consumption (never drinker, former drinker, current drinker [23–45 g/week, 46–68 g/week, ≥ 69 g/week]) , smoking status (never smoker, former smoker, current smoker), body mass index, HDL-cholesterol, triglycerides, HbA1c, and GFR. Platelet tertiles: For men < 19.6 × 104/μL for T1, 19.6–23.5 × 104/μL for T2, > 23.5 × 104/μL for T3. For women < 20.9 × 104/μL for T1, 20.9–24.6 × 104/μL for T2, > 24.6 × 104/μL for T3. The 1 standard deviation (SD) increment of platelets was 5.2 × 104/μL for men and 4.8 × 104/μL for women. Reticulocyte tertiles: For men, < 4.464 × 104 cells/μL for T1, 4.464–5.796 × 104/cells/μL for T2, > 5.796 × 104/μL for T3. For women, < 4.0 × 104 cells/μL for T1, 4.0–5.29 × 104 cells/μL for T2, > 5.29 × 104 cells/μL for T3. The increments of 1 standard deviation (SD) in reticulocytes are 2.0 × 104 cells/μL for men and 1.6 × 104 cells/μL for women.