Table 6.
Odds ratios (OR) and 95% confidence intervals (CI) for never drinker in relation to rs671 genotype.
rs671 | |||||
---|---|---|---|---|---|
Major homo (G/G) | Hetero (G/A) | Minor homo (A/A) | p for trend | MAF | |
Men | |||||
No. of participants (%) | 296 (59.9) | 164 (33.2) | 34 (6.9) | < 0.05* | |
No. of expectations (%) | 289.24 (58.6) | 177.52 (35.9) | 27.24 (5.5) | ||
No. of cases (%) | 38 (12.8) | 71 (43.3) | 28 (82.4) | ||
Age-adjusted | 1.00 | 5.21 (3.28, 8.27) | 33.09 (12.79, 85.61) | < 0.001 | 5.47 (3.78, 7.92) |
Women | |||||
No. of participants (%) | 511 (62.4) | 255 (31.1) | 53 (6.5) | ≥ 0.05* | |
No. of expectations (%) | 497.78 (60.8) | 281.44 (34.4) | 39.78 (4.9) | ||
No. of cases (%) | 376 (73.6) | 229 (89.8) | 52 (98.1) | ||
Age-adjusted | 1.00 | 3.27 (2.07, 5.16) | 20.05 (2.74, 146.91) | < 0.001 | 3.49 (2.32, 5.25) |
MAF: minor allele frequency.
*Hardy–Weinberg equilibrium p-values.