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. 2020 Aug 25;10:14148. doi: 10.1038/s41598-020-71031-9

Table 6.

Odds ratios (OR) and 95% confidence intervals (CI) for never drinker in relation to rs671 genotype.

rs671
Major homo (G/G) Hetero (G/A) Minor homo (A/A) p for trend MAF
Men
No. of participants (%) 296 (59.9) 164 (33.2) 34 (6.9)  < 0.05*
No. of expectations (%) 289.24 (58.6) 177.52 (35.9) 27.24 (5.5)
No. of cases (%) 38 (12.8) 71 (43.3) 28 (82.4)
Age-adjusted 1.00 5.21 (3.28, 8.27) 33.09 (12.79, 85.61)  < 0.001 5.47 (3.78, 7.92)
Women
No. of participants (%) 511 (62.4) 255 (31.1) 53 (6.5)  ≥ 0.05*
No. of expectations (%) 497.78 (60.8) 281.44 (34.4) 39.78 (4.9)
No. of cases (%) 376 (73.6) 229 (89.8) 52 (98.1)
Age-adjusted 1.00 3.27 (2.07, 5.16) 20.05 (2.74, 146.91)  < 0.001 3.49 (2.32, 5.25)

MAF: minor allele frequency.

*Hardy–Weinberg equilibrium p-values.