Fig. 4. Multitask model indicates current test performances could imply future cognitive status.

The area under receiver operating characteristic curve (AUC) of the multitask model prediction on unseen data with each task predicting the participants’ cognitive status at n^th years after the first visit using only their first visit and biological data (a). The median (Q2), the first and third quantile (Q1 and Q3), and the minimum and maximums (Q1−1.5IQR and Q3 + 1.5IQR) are at the center line, bounds, and the whiskers of the box plots. The heatmap depicting the magnitude of components from PD-NCI and PDD classification models, highlighting the importance of many of the cognitive tests in the prediction of future cognitive status. The positive components in each model are associated with higher probability of that model’s diagnosis (b).