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. 2020 Aug 25;10:14162. doi: 10.1038/s41598-020-71025-7

Table 5.

Antimicrobial activity of ceftazidime (CAZ) alone and in combination with di-F-Q against 50 clinical isolates of P. aeruginosa.

Antimicrobial Agent MIC50 (mg/l)a MIC90 (mg/l)b CLSIc breakpointd
%S %I %R
CAZ alone (n = 50) 4 > 32 78.4 5.9 15.7
CAZ + di-F-Q (32 mg/L) (n = 50) 2 8 94.1 3.9 2.0

aMIC required to inhibit 50% of isolates.

bMIC required to inhibit 90% of isolates.

cClinical Laboratory Standards Institute.

dS (Sensitive): MIC ≤ 8, I (Intermediate): MIC = 16, R (Resistant): MIC ≥ 32 (mg/l).