Table 5.
Antimicrobial activity of ceftazidime (CAZ) alone and in combination with di-F-Q against 50 clinical isolates of P. aeruginosa.
| Antimicrobial Agent | MIC50 (mg/l)a | MIC90 (mg/l)b | CLSIc breakpointd | ||
|---|---|---|---|---|---|
| %S | %I | %R | |||
| CAZ alone (n = 50) | 4 | > 32 | 78.4 | 5.9 | 15.7 |
| CAZ + di-F-Q (32 mg/L) (n = 50) | 2 | 8 | 94.1 | 3.9 | 2.0 |
aMIC required to inhibit 50% of isolates.
bMIC required to inhibit 90% of isolates.
cClinical Laboratory Standards Institute.
dS (Sensitive): MIC ≤ 8, I (Intermediate): MIC = 16, R (Resistant): MIC ≥ 32 (mg/l).