Figure 1.
The central metabolism of P. putida KT2440 with the Ehrlich pathway. Abbreviations (coding genes are given in brackets): G6P: glucose‐6‐phosphate 2‐KG: 2‐ketogluconate, 2‐K6PG: 2‐keto‐6‐phosphogluconate, 6‐PG: 6‐phosphogluconate, 2‐KDPG: 2‐keto‐3‐deoxy‐6‐phosphogluconate, G3P: glyceraldehyde‐3‐phosphate, 1,3‐bPG: 1,3‐bisphosphoglycerate, 3‐PG: 3‐phosphoglycerate, 2‐PG: 2‐phosphoglycerate, PEP: phosphoenolpyruvate, DHAP: dihydroxyacetone‐phosphate, F‐1,6‐bP: fructose‐1,6‐bisphosphate, F6P: fructose‐6‐phosphate, CoA: co‐enzyme A, Gcd: glucose dehydrogenase (gcd), gad: gluconate 2‐dehdyrogenase (gad), PQQ: pyrroloquinoline quinone, Glk: glucokinase (glk), Zwf: glucose‐6‐phosphate 1‐dehydrogenase (zwf‐1, zwf‐2, zwf‐3), GnuK: gluconate kinase (gnuK), KguD: 2‐6‐phosphoketogluconate reductase (kguD), KguK: 2‐ketogluconate kinase (kguK), Edd: 6‐phosphogluconate dehydratase (edd), Eda: 2‐keto‐3‐deoxy‐6‐phosphogluconate aldolase (eda), IlvHI/AlsS: acetolactacte synthase (ilvHI/alsS), IlvC: ketolacid reductoisomerase (ilvC), IlvD: dihydroxyacid dehydratase (ilvD), KivD: ketoacid decarboxylase (kivD), Bkd: branched‐chain ketoacid dehydrogenase complex (bkd), Yqhd: aldehyde reductase (yqhD), AldH: aldehdye dehdyrogenases, PntAB: pyridine nucleotide transhydrogenase (membrane bound) (pntAB), SthA: pyridine nucleotide transhydrogenase (soluble) (sthA)