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. 2020 Mar 9;18(3):e05991. doi: 10.2903/j.efsa.2020.5991

Table 9.

Existing carcinogenicity evaluations for short‐chain chlorinated paraffins (SCCPs) and long‐chain chlorinated paraffins (LCCPs)

Organisation Outcome Remarks
SCCPs
NTP (1986a, 2016)

C12, 60% chlorination:

Clear evidence of carcinogenicity for F344/N rats and for B6C3F1 mice (NTP, 1986a)

Reasonably anticipated to be human carcinogens based on sufficient evidence of carcinogenicity from studies in experimental animals (NTP, 2016)

 
IARC (1990)

C12, 60% chlorination:

Group 2B (possibly carcinogenic to humans)

There is sufficient evidence for the carcinogenicity in experimental animals. No data were available from studies in humans
LCCPs
Organisation Outcome Remarks
NTP (1986b)

C23, 43% chlorination:

No evidence of carcinogenicity for male F344/N rats, equivocal evidence of carcinogenicity for female F344/N rats, clear evidence of carcinogenicity for male B6C3F1 mice, equivocal evidence of carcinogenicity for female B6C3F1 mice

 
IARC (1990)

C23, 43% chlorination:

No IARC Group assigned

There is limited evidence for the carcinogenicity in experimental animals. No data were available from studies in humans