Figure 6.

Sel-TCP-Seq Dissects REI-Mediated Control of ATF4 mRNA Translation

(A) Human unselected 40S and 80S FP coverage frequency along the ATF4 5′ UTR (schematic with regulatory elements shown on top). uORF locations are emphasized by vertical gray shading. Averages of replicates 1, 2, and 3 are shown.

(B) As (A) but showing eIF3b::40S FP coverage frequency (the unselected 40S track is indicated as a dashed line). Averages of replicates 1 and 3 are shown.

(C) Schematic of ATF4 translational control.

Error bars in (A) and (B) indicate ± standard deviation.