Table 4.

In vitro UDS test results (DMSO=dimethyl sulfoxide)

Type of test	Experimental test system	Test substance	Exposure conditions	Result	WG considerations and conclusion	Reference
UDS in vitro	Primary rat hepatocytes	triazine amine CGA 150 829 tech (97.6%)	Six concentrations tested from 1 to 100 μg/mL in replicated experiments 100 μg/mL highest usable concentration (1% of DMSO solution at 10 mg/mL)	No increase in net nuclear grain counts at any concentration in replicated experiments Net positive response with positive control	GLP compliant According to OECD TG 482 (1987) Negative	Hertner (1988)
UDS in vitro	Human fibroblasts	triazine amine CGA 150 829 tech (97.6%)	Six concentrations tested from 1 to 100 μg/mL in replicated experiments 100 μg/mL highest usable concentration (1% of DMSO solution at 10 mg/mL)	No increase in net nuclear grain counts at any concentration in replicated experiments Net positive response with positive control	GLP compliant According to OECD TG 482 (1987) Negative	Meyer (1988)