| EFSA risk assessment area | Microorganism species/strain | Intended use | EFSA Question numbera and EFSA webpage linkb | Additional information provided by the EFSA Scientific Unit | Previous QPS status of the respective TU?c | To be evaluated? yes or nod |
|---|---|---|---|---|---|---|
| Bacteria | ||||||
| Feed additives | Bacillus amyloliquefaciens BS918, Bacillus amyloliquefaciens BS1013, Bacillus subtilis BS3BP5 | Zootechnical additives/Digestibility enhancers | EFSA‐Q‐2019‐00480 | Syncra® SWI 201 TPT (Bacillus amyloliquefaciens BS918, Bacillus amyloliquefaciens BS1013, Bacillus subtilis BS3BP5 and Protease) | Yes | No |
| Feed additives | Bacillus amyloliquefaciens PTA‐6507, Bacillus amyloliquefaciens NRRL B‐50013 and Bacillus amyloliquefaciens NRRL B‐50104 | Zootechnical additives/Gut flora stabilisers | EFSA‐Q‐2019‐00457 | Enviva® PRO 202 GT (Bacillus amyloliquefaciens PTA‐6507, Bacillus amyloliquefaciens NRRL B‐50013 and Bacillus amyloliquefaciens NRRL B‐50104) | Yes | No |
| Feed additives | Bacillus coagulans DSM 32016 |
Zootechnical additive Gut flora stabiliser |
EFSA‐Q‐2019‐00313 | TechnoSpore® (Bacillus coagulans DSM 32016) | Yes | No |
| Feed additives | Bacillus licheniformis DSM 28710 (BL11) | Zootechnical additives/Gut flora stabilisers | EFSA‐Q‐2019‐00525 | Already authorised for other target species | Yes | No |
| Feed additives | Bacillus subtilis C‐3102, DSM 15544 |
Zootechnical additive Gut flora stabiliser |
EFSA‐Q‐2019‐00370/FAD‐2019‐0037 |
Calsporin® (Bacillus subtilis C‐3102, DSM 15544) Application for renewal |
Yes | No |
| Feed additives | Bacillus subtilis PB6 (Bacillus subtilis ATCC PTA‐6737) |
Zootechnical additives/Gut flora stabilisers Bacillus subtilis PB6 (Bacillus subtilis ATCC PTA‐6737) |
EFSA‐Q‐2019‐00410 FAD‐2019‐0017 |
Trade name: Bacillus subtilis PB6 | Yes | No |
| Plant protection products | Bacillus subtilis RTI477 | EFSA‐Q‐2019‐00341 | Yes | No | ||
| Plant protection products | Bacillus velezensis RTI301 |
Fungicide Bacillus velezensis RTI301 and Bacillus subtilis RTI477 are the microbial active ingredients in the formulated product F4034‐5, efficacious against seed‐ and soil‐borne pathogens such as Rhizoctonia solani, Phytium spp., Phytophtora capsici, Sclerotinia sclerotiorum, Fusarium spp., Phoma lingam and Plasmodiophora brassiceae |
EFSA‐Q‐2019‐00363 | No | Yes | |
| Feed additives | Corynebacterium glutamicum DSM32932 |
Nutritional additives Amino acids |
EFSA‐Q‐2019‐00331/FAD‐2019‐0028 | L‐lysine monohydrochloride produced by fermentation using genetically modified Corynebacterium glutamicum DSM32932 | Yes | No |
| Feed additives | Corynebacterium glutamicum KCCM 80189 |
Nutritional additive L‐Isoleucine produced by fermentation with Corynebacterium glutamicum KCCM 80189es Amino acids |
EFSA‐Q‐2019‐00293 | L‐Isoleucine produced by fermentation with Corynebacterium glutamicum KCCM 80189 | Yes | No |
| Corynebacterium glutamicum KCCM80183 | Nutritional additives/Amino acids |
EFSA‐Q‐2019‐ 00411 FAD‐2019‐0016 |
L‐Lysine monohydrochloride/Concentrated liquid L‐Lysine/L‐Lysine sulfate produced by fermentation with Corynebacterium glutamicum KCCM80183 | Yes | No | |
| Feed additives | Corynebacterium stationis |
Sensory additives Flavouring compounds IMP (disodium 5′‐inosinate) produced by fermentation with Corynebacterium ammoniagenes KCCM 80161 |
EFSA‐Q‐2019‐00040 | Disodium 5′‐inosinate feed grade is a highly purified product and does not contain any microorganisms. After the fermentation, the cells of the production strain Corynebacterium ammoniagenes KCCM80161 are eliminated by filtration and centrifugation from the fermentation broth | No | Yes |
| Food enzymes, food additives and flavourings | Cupriavidus necator | Production of food contact material | EFSA‐Q‐2017‐00412 | The strain expresses the enzyme PHBH synthase derived from Aeromonas caviae, used for the synthesis of a copolymer | No | Yes |
| Food enzymes, food additives and flavourings | Escherichia coli (Strain K‐12 W3110) | Production of food enzyme D‐allulose 3‐epimerase | EFSA‐Q‐2019‐00445 | Genetically modified strain | No | No |
| Novel foods | Escherichia coli (W3110 – TK0) K12 ‐derivative | D‐psicose‐3‐epimerase, produced by a GMO derivative from E. coli K12, is used in the synthesis of allulose (novel food) | EFSA‐Q‐2019‐00 | The novel food is allulose. An application for the FE has been submitted to EFSA (EFSA‐2016‐00211) | No | No |
| Feed additives | Escherichia coli AG3149 | Nutritional additives, Amino acids and Sensory additive, Flavouring compound | EFSA‐Q‐2019‐00361/FAD‐2019‐0035 |
L‐isoleucine produced by fermentation of Escherichia coli AG3149 Application for renewal and extension of use |
No | No |
| Food enzymes, food additives and flavourings | Escherichia coli BL21 (DE3) | Production of food enzyme OBT‐001 | EFSA‐Q‐2019‐00444 | Genetically modified strain | No | No |
| Novel foods | Escherichia coli BL21 (DE3) | Production of the novel food Lacto‐N‐neotetraose (LNnT) | EFSA‐Q‐2019‐00448 | Extension of the present specifications for LNnT produced by genetically modified (GM) E. coli K‐12 to include LNnT produced by GM E. coli BL21 (DE3) | No | No |
| Food enzymes, food additives and flavourings | Escherichia coli production strains (LE1B1090) | Production of enzymes (UDP‐glucosyltransferases and a sucrose synthase) derived from GM strains of E. coli K‐12 | EFSA‐Q‐2019‐00499 | Amendment of specification of food additive steviol glycosides produced by enzymatic conversion of highly purified reb A and/or stevioside from stevia leaf extract | No | No |
| Food enzymes, food additives and flavourings | Genetically modified strain of Bacillus licheniformis (strain NZYM‐VR) | Production of food enzyme phospholipase C | EFSA‐Q‐2019‐00442 | Yes | No | |
| Feed additives | Komagataella phaffii appaT75 (CGMCC 12056) | Zootechnical additives/Digestibility enhancers | EFSA‐Q‐2019‐00461 | APSA PHYTAFEED® 20,000 GR, APSA PHYTAFEED® 20,000 L (6‐phytase produced by genetically modified Komagataella phaffi appaT75 (CGMCC 12056)) | Yes | No |
| Feed additive | Lactobacillus parafarraginis DSM 32962 | Technological additives/Silage additive | EFSA‐Q‐2019‐00626/FAD‐2019‐0062 | Non‐GMO lactobacillus/WGS received as part of the dossier | No | Yes |
| Feed additives | Lactobacillus plantarum CECT 8350 and Lactobacillus reuteri CECT 8700 | Zootechnical additives/Gut flora stabilisers | EFSA‐Q‐2019‐00487 | AQ02® (Lactobacillus plantarum CECT 8350 and Lactobacillus reuteri CECT 8700) | Yes | No |
| Food enzymes, food additives and flavourings | Paenibacillus illinoisensis | Production of food enzyme | EFSA‐Q‐2016‐00523 | The production strain is used in the manufacturing of cyclomaltodextrin glucanotransferase. The initial submission of the application identified the strain as Bacillus circulans. B. circulans group 6 has been reclassified as the new species P. illinoisensis | No | Yes |
| Feed additives | Pantoea ananatis ‐ Strain NITE BP‐02525 strain | Nutritional additive amino acids, their salts and analogues and sensory additive flavouring compound | EFSA‐Q‐2019‐00332/FAD‐2019‐0026 | L‐cystine produced by fermentation using strain NITE BP‐02525 strain which has been derived from Pantoea ananatis | No | Yes |
| Food enzymes, food additives and flavourings | Parageobacillus thermoglucosidasius | Production of food enzyme alpha‐amylase | EFSA‐Q‐2016‐00145 |
The food enzyme is an Alpha‐amylase It was initially designated by the applicant as Geobacillus stearothermophilus which is recommended for QPS. However, new data provided after a request for a 16S rRNA analysis, demonstrated quite unambiguously that the production strain is a strain of Geobacillus thermoglucosidans, closely related to G. stearothermophilus but not on the QPS list |
No | Yes |
| Feed additives | Pediococcus pentosaceus DSM 16244 |
Technological additives Silage additive |
EFSA‐Q‐2019‐00369/FAD‐2019‐0039 | Application for renewal | Yes | No |
| Novel foods | Protaminobacter rubrum strain CBS 574.77 us | For the production of a Novel Food ’Isomaltulose syrup’ | EFSA‐Q‐2018‐00609 | Request for a scientific opinion as an NF; see also short published summary of this application: https://ec.europa.eu/food/sites/food/files/safety/docs/novel-food_sum_ongoing-app_isomaltulose-syrup.pdf | No | Yes |
| Food enzymes, food additives and flavourings | Rhodococcus aetherovorans strain USA‐AN012 | Production of Food Additives |
EFSA‐Q‐2011‐00612 EFSA‐Q‐2011‐00613 EFSA‐Q‐2011‐00614 EFSA‐Q‐2011‐00615 EFSA‐Q‐2011‐00616 EFSA‐Q‐2011‐00617 EFSA‐Q‐2011‐00637 |
The production strain is used in the manufacturing of tartaric acid | No | Yes |
| Food enzymes, food additives and flavourings | Rhodococcus ruber strain CM001 | Production of Food Additives |
EFSA‐Q‐2011‐00612 EFSA‐Q‐2011‐00613 EFSA‐Q‐2011‐00614 EFSA‐Q‐2011‐00615 EFSA‐Q‐2011‐00616 EFSA‐Q‐2011‐00617 EFSA‐Q‐2011‐00637 |
The production strain is used in the manufacturing of tartaric acid | No | Yes |
| Food enzymes, food additives and flavourings | Sphingomonas paucimobilis | Production of Food Additives | EFSA‐Q‐2011‐00517 | The production strain is used in the manufacturing of Gellan Gum | No | No |
| Filamentous fungi | ||||||
| Feed additives | Aspergillus aculeatus CBS589.94 | Zootechnical additives/Digestibility enhancers | EFSA‐Q‐2019‐00528 | RONOZYME® VP (CT) and RONOZYME® VP (L) (endo‐1,3(4)‐β‐glucanase (IUB No 3.2.1.6)) produced by Aspergillus aculeatus CBS589.94 | No | No |
| Feed additives | Aspergillus niger CGMCC No.5751 |
Zootechnical additives/Other zootechnical additives Renewal authorisation |
EFSA‐Q‐2019‐00590/FAD‐2019‐0054 | AviPlus® is a preparation of sorbic acid, citric acid, thymol and vanillin. Citric acid is produced by a non‐GMO strain of A. niger | No | No |
| Novel foods | Aspergillus oryzae strain GL 470 | Beta‐galactosidase as a novel food | EFSA‐Q‐2019‐00257 | The production of beta‐galactosidase via fermentation of a stable non‐GMO Aspergillus oryzae strain | No | No |
| Feed additives | Trichoderma reesei RF11556 |
Zootechnical additives Digestibility enhancers |
EFSA‐Q‐2019‐00330/FAD‐2019‐0029 |
ECONASE® XT (endo‐1,4‐beta‐xylanase) produced by fermentation of genetically modified Trichoderma reesei RF11556 Change in the production strain |
No | No |
| Feed additives | Trichoderma reesei RF7265 |
Zootechnical additives Digestibility enhancers |
EFSA‐Q‐2019‐00333/FAD‐2019‐0027 |
FINASE® EC (6‐phytase) produced by fermentation of genetically modified Trichoderma reesei RF7265 Application for renewal |
No | No |
| Food enzymes, food additives and flavourings | Moniliella pollinis | Production of food flavourings | EFSA‐Q‐2011‐00730 | The production strain is used in the manufacturing of erythritol | No | No |
| Food enzymes, food additives and flavourings | Moniliella megachilensis | Production of food flavourings | EFSA‐Q‐2011‐00730 | The production strain is used in the manufacturing of erythritol | No | No |
| Yeasts | ||||||
| Novel food | Euglena gracilis | Biomass of Euglena gracilis | EFSA‐Q‐2019‐00593 | The novel food is Paramylon, derived from proprietary strain of Euglena gracilis | Yes | No |
| Food enzymes, food additives and flavourings | Hamamotoa singularis (homotypic name as Sporobolomyces singularis) | Food enzyme: Beta‐galactosidase from Sporobolomyces singularis (YIT 10047) | EFSA‐Q‐2016‐00529 | No | Yes | |
| Food enzymes, food additives and flavourings | Kodamaea ohmeri | Production of food flavourings | EFSA‐Q‐2011‐00729 | The production strain is used in the manufacturing of xylitol | No | Yes |
| Feed additives | Komagataella pastoris (CECT 13094) |
Zootechnical additives Digestibility enhancers, substances which favourably affect the environment |
EFSA‐Q‐2019‐00430 FAD‐2019‐0041 |
Preparation of 3‐phytase produced by Komagataella pastoris (CECT 13094) presented in solid (FSF10000) and liquid (FLF1000) forms. The confirmation of the identity of the GMM was conducted using Microbial Identification by DNA sequencing. | Yes | No |
| Feed additives | Komagataella pastoris appaT75 (CGMCC 12056) |
Zootechnical additive Digestibility enhancer 6‐ phytase produced by a genetically modified yeast |
EFSA‐Q‐2019‐00312/FAD‐2019‐0021 | APSA PHYTAFEED® 20,000 GR, APSA PHYTAFEED® 20,000 L (6‐phytase) | Yes | No |
| Feed additives | Komagataella phaffi DSM 32854 | Zootechnical additives/Digestibility enhancers | EFSA‐Q‐2019‐00479 | OptiPhos® PLUS (6 phytase produced by genetically modified Komagataella phaffi DSM 32854) | Yes | No |
| Feed additives |
Komagataella phaffii strain BSY‐0007 (DSM 32854) (GMO production organism) Komagataella phaffii BG10 (Recipient organism) |
OptiPhos Plus is a 6‐phytase classified under category 4 ‘zootechnical additives’, functional group a ‘digestibility enhancers’, subclassification ‘enzymes’ as specified in Annex I to Regulation (EC) No 1831/2003 |
EFSA‐Q‐2019‐00303 FAD‐2019‐0023 |
GMO production organism: Komagataella phaffii strain BSY‐0007 (DSM 32854) | Yes | No |
| Feed additives | Komagatella phaffii/Pichia pastoris DSM 32159) | Technological additives/Substances for the reduction of the contamination of feed with mycotoxins | EFSA‐Q‐2019‐00624/FAD‐2019‐0061 | FUMzyme® (fumonisin esterase) produced by a genetically modified strain of Komagatella phaffii | Yes | No |
| Feed additives | Komagatella phaffii DSM 32854) | Zootechnical additives/Digestibility enhancers | EFSA‐Q‐2019‐00526 | OptiPhos® PLUS (6 phytase) produced by a genetically modified strain of Komagatella phaffii | Yes | No |
| Feed additives | Saccharomyces cerevisiae MUCL 39885 |
Zootechnical additives Gut flora stabilisers Saccharomyces cerevisiae MUCL 39885 |
EFSA‐Q‐2019‐00219 | Saccharomyces cerevisiae MUCL 39885 | Yes | No |
| Food enzymes, food additives and flavourings | Zygosaccharomyces rouxii | Production of food flavourings | EFSA‐Q‐2011‐00723 | The production strain is used in the manufacturing of mannitol | No | Yes |
| Viruses | ||||||
| Plant protection products | Phthorimaea operculella granulovirus (PhopGV) | Insecticide with activity against larvae of the tomato leafminer Tuta absoluta and the potato tuber moth Phthorimae operculella | EFSA‐Q‐2019‐00382 | Belongs to the group of Betabaculovirus | Yes | No |
| Algae | ||||||
| Novel food | Schizochytrium limacinum strain WZU477 (synonym of Aurantiochytrium limacinum) | Modification to include Schizochytrium limacinum strain WZU477 for the production of Docosahexaenoic acid‐rich oil | EFSA‐Q‐2019‐00306 | Novel food already authorised | No | Yes |
| Novel food | Schizochytrium sp | Oil rich in Docosahexaenoic acid from Schizochytrium sp | EFSA‐Q‐2019‐00323 | Novel food already authorised | No | Yes |
| Novel food | Schizochytrium sp. | Production of DHA‐rich oil (BioDHA) from Schizochytrium sp. as a novel food | EFSA‐Q‐2019‐00548 | Extension of use in infant and follow‐on formulae | No | Yes |
| Novel food | Tetraselmis chuii | Dried Tetraselmis chuii microalgae as a novel food | EFSA‐Q‐2019‐00535 | Modification of the specifications of the dried Tetraselmis chuii microalgae, already authorised | No | Yes |
To find more details on specific applications please access the EFSA website ‐ Register of Questions: http://registerofquestions.efsa.europa.eu/roqFrontend/ListOfQuestionsNoLogin?0&panel=ALL
Where no link is given this means that the risk assessment has not yet been published.
Included in the QPS list as adopted in December 2016 (EFSA BIOHAZ Panel, 2017a) and respective updates which include new additions (latest: EFSA BIOHAZ Panel, 2019b).
In the current Panel Statement.