Review of the existing maximum residue levels for metaflumizone according to Article 12 of Regulation (EC) No 396/2005

. 2020 Jun 17;18(6):e06123. doi: 10.2903/j.efsa.2020.6123

Primary crops (available studies)	Crop groups	Crop(s)	Application(s)	Sampling (DAT)	Comment/Source
	Fruit crops	Tomato	Foliar: 6 × 331–378 g a.s./ha, 7 days interval (from early fruiting)	0, 7	Benzonitrile (B‐label) ¹⁴C‐metaflumizone or trifluoromethoxyphenyl (T‐label) ¹⁴C‐metaflumizone Studies performed both in field and in glasshouse (United Kingdom, 2012)
Leafy crops	White cabbage	Foliar: 4 × 280 g a.s./ha, 7 days interval (from 106 days after planting)	0, 3, 7	B‐labelled or T‐labelled metaflumizone. Studies performed in glasshouse conditions (United Kingdom, 2012)
Pulses/oilseeds	Cotton seeds	Foliar: 6 × 307–350 g a.s./ha, 7 days interval (from mid‐flowering)	21	B‐labelled or T‐labelled metaflumizone (United Kingdom, 2012)

Primary crops (available studies)

Crop groups

Crop(s)

Application(s)

Sampling (DAT)

Comment/Source

Fruit crops

Tomato

Foliar: 6 × 331–378 g a.s./ha, 7 days interval (from early fruiting)

0, 7

Benzonitrile (B‐label) ¹⁴C‐metaflumizone or trifluoromethoxyphenyl (T‐label)

¹⁴C‐metaflumizone

Studies performed both in field and in glasshouse (United Kingdom, 2012)

Leafy crops

White cabbage

Foliar: 4 × 280 g a.s./ha, 7 days interval (from 106 days after planting)

0, 3, 7

B‐labelled or T‐labelled metaflumizone. Studies performed in glasshouse conditions (United Kingdom, 2012)

Pulses/oilseeds

Cotton seeds

Foliar: 6 × 307–350 g a.s./ha, 7 days interval (from mid‐flowering)

B‐labelled or T‐labelled metaflumizone (United Kingdom, 2012)

Crop groups	Crop(s)	Application(s)	PBI (DAT)	Comment/Source
Root/tuber crops	Radish	Bare soil: 2 × 560 g a.s./ha, 20 days interval	30, 60/62, 120, 365	B‐labelled or T‐labelled metaflumizone (United Kingdom, 2012)
Root/tuber crops	Radish	Bare soil: 1 × 1.168 kg a.s./ha	30	B‐labelled or T‐labelled metaflumizone (United Kingdom, 2012)
Leafy crops	Lettuce	Bare soil: 2 × 560 g a.s./ha, 20 days interval	30, 60/62, 120, 365	B‐labelled or T‐labelled metaflumizone (United Kingdom, 2012)
Leafy crops	Lettuce	Bare soil: 1 × 1.168 kg a.s./ha	30	B‐labelled or T‐labelled metaflumizone (United Kingdom, 2012)
Cereal (small grain)	Wheat	Bare soil: 2 × 560 g a.s./ha, 20 days interval	30, 60/62, 120, 365	B‐labelled or T‐labelled metaflumizone (United Kingdom, 2012)
Cereal (small grain)	Wheat	Bare soil: 1 × 1.168 kg a.s./ha	30	B‐labelled or T‐labelled metaflumizone (United Kingdom, 2012)

Processed commodities (hydrolysis study)	Conditions	Stable?	Comment/Source
	Pasteurisation (20 min, 90°C, pH 4)	Yes	Metaflumizone (sum of E‐ and Z‐isomers) is stable in both studies performed with B‐label or T‐label (77–78% of applied radioactivity; AR) Degradation products observed with B‐label study, mainly M320I04 (15% AR) (United Kingdom, 2012)
Baking, brewing and boiling (60 min, 100°C, pH 5)	No	Metaflumizone (sum of E‐ and Z‐isomers) is stable in the study performed with T‐label. However, not with B‐label (62% AR) Degradation products observed with B‐label study, mainly M320I04 (25% AR) (United Kingdom, 2012)
Sterilisation (20 min, 120°C, pH 6)	Yes	Metaflumizone (sum of E‐ and Z‐isomers) is stable in both studies performed with B‐label or T‐label (89–94% AR) No degradation products observed (United Kingdom, 2012)

Processed commodities (hydrolysis study)

Conditions

Stable?

Comment/Source

Pasteurisation (20 min, 90°C, pH 4)

Yes

Metaflumizone (sum of E‐ and Z‐isomers) is stable in both studies performed with B‐label or T‐label (77–78% of applied radioactivity; AR)

Degradation products observed with B‐label study, mainly M320I04 (15% AR) (United Kingdom, 2012)

Baking, brewing and boiling (60 min, 100°C, pH 5)

Metaflumizone (sum of E‐ and Z‐isomers) is stable in the study performed with T‐label. However, not with B‐label (62% AR)

Degradation products observed with B‐label study, mainly M320I04 (25% AR) (United Kingdom, 2012)

Sterilisation (20 min, 120°C, pH 6)

Yes

Metaflumizone (sum of E‐ and Z‐isomers) is stable in both studies performed with B‐label or T‐label (89–94% AR)

No degradation products observed (United Kingdom, 2012)