Parameter | Sex | Group (mean ± standard error) | ||||
---|---|---|---|---|---|---|
SDC Control | PSE control | 0.2% POC | 0.6% POC | 1.6% POC | ||
Body weight (g) (end of study) | m | 420.4 ± 5.9 | 410.9 + 6.8 | 423.6 ± 8.8 | 425.2 ± 8.4 | 419.2 ± 6.4 |
f | 226.9 ± 4.0 | 226.9 ± 4.1 | 229.7 ± 5.5 | 233.6 ± 3.6 | 220.1 ± 3.9 | |
Absolute liver weight (g) | m | 15.38 ± 0.31 | 14.72 ± 0.41 | 14.85 ± 0.42 | 15.38 ± 0.41 | 15.83 ± 0.30 |
f | 7.34 ± 0.17 | 7.41 ± 0.17 | 7.52 ± 0.17 | 7.86 ± 0.19 | 8.29 ± 0.18b,d | |
Relative liver weight (g/kg bw) | m | 36.6 ± 0.5 | 35.8 ± 08 | 35.0 ± 0.6 | 36.1 ± 05 | 37.8 ± 0.5 |
f | 32.3 ± 0.5 | 32.7 ± 0.5 | 32.8 ± 0.6 | 33.6 ± 0.5 | 37.6 ± 0.3b,d | |
γ‐GT (U/L) | m | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.1 ± 0.0 | 0.0 ± 0.0 | 0.1 ± 0.0 |
f | 0.3 ± 0.1 | 0.3 ± 0.1 | 0.3 ± 0.1 | 0.3 ± 0.1 | 1.2 ± 0.2b,d | |
ALP | m | 119 ± 5b | 150 ± 6d | 150 ± 7d | 148 ± 6d | 155 ± 4d |
f | 122 ± 6b | 158 ± 6d | 154 ± 8c | 155 ± 9c | 164 ± 10d | |
Albumin | m | 42 ± 0a | 43 ± 0c | 43 ± 0b | 43 ± 0 | 44 ± 0b,c |
f | 46 ± 0 | 48 ± 0 | 48 ± 0 | 48 ± 0a | 48 ± 0a | |
Thrombocyte count (× 109/L) | m | 794 ± 13 | 767 ± 20 | 831 ± 16a | 827 ± 15a | 876 ± 15b,d |
f | 844 ± 18 | 812 ± 19 | 825 ± 16 | 828 ± 17 | 894 ± 23b | |
PTT (s) | m | 39.7 ± 0.5b | 37.1 ± 0.4d | 37.4 ± 0.5d | 37.2 ± 0.4d | 37.3 ± 0.4d |
f | 35.4 ± 0.4 | 34.0 ± 0.3 | 34.4 ± 0.4 | 34.1 ± 0.4 | 34.0 ± 0.6 | |
Total cholesterol | m | 2.15 ± 0.08c | 2.60± 0.06d | 2.60 ± 0.10d | 2.52 ± 0.05d | 2.28 ± 0.08a |
(mmol/L) | f | 1.76 ± 0.05b | 2.18 ± 0.07d | 2.06 ± 0.05d | 2.04 ± 0.06d | 2.05 ± 0.05d |
HDL | m | 1.41 ± 0.06b | 1.72 ± 0.05d | 1.75 ± 0.07d | 1.73 ± 0.05d | 1.69 ± 0.06d |
(mmol/L) | f | 1.36 ± 0.04b | 1.63 ± 0.06d | 1.55 ± 0.05c | 1.60 ± 0.03d | 1.74 ± 0.05d |
Non‐HDL | m | 0.74 ± 0.04 | 0.87 ± 0.03 | 0.85 ± 0.06 | 0.79 ± 0.04 | 0.59 ± 0.03c,d |
(mmol/L) | f | 0.40 ± 0.03a | 0.55 ± 0.04 | 0.52 ± 0.04c | 0.44 ± 0.05a | 0.31 ± 0.02b |
Triglycerides | m | 2.36 ± 0.19 | 2.10 ± 0.20 | 2.04 ± 020 | 1.85 ± 0.15 | 1.25 ± 0.07b,c |
(mmol/L) | f | 1.32 ± 0.16 | 1.40 ± 0.17 | 1.37 ± 0.16 | 1.14 ± 0.12 | 0.71 ± 0.04a,c |
POC: plant sterol oxidation concentrate.
p < 0.05 (vs. PSE = plant sterol esters control).
p < 0.01 (vs. PSE control).
p < 0.05 (vs. SDC = standard diet control).
p < 0.01 (vs. SDC diet).