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. 2020 Jun 30;18(6):e06135. doi: 10.2903/j.efsa.2020.6135
Parameter Sex Group (mean ± standard error)
SDC Control PSE control 0.2% POC 0.6% POC 1.6% POC
Body weight (g) (end of study) m 420.4 ± 5.9 410.9 + 6.8 423.6 ± 8.8 425.2 ± 8.4 419.2 ± 6.4
f 226.9 ± 4.0 226.9 ± 4.1 229.7 ± 5.5 233.6 ± 3.6 220.1 ± 3.9
Absolute liver weight (g) m 15.38 ± 0.31 14.72 ± 0.41 14.85 ± 0.42 15.38 ± 0.41 15.83 ± 0.30
f 7.34 ± 0.17 7.41 ± 0.17 7.52 ± 0.17 7.86 ± 0.19 8.29 ± 0.18b,d
Relative liver weight (g/kg bw) m 36.6 ± 0.5 35.8 ± 08 35.0 ± 0.6 36.1 ± 05 37.8 ± 0.5
f 32.3 ± 0.5 32.7 ± 0.5 32.8 ± 0.6 33.6 ± 0.5 37.6 ± 0.3b,d
γ‐GT (U/L) m 0.0 ± 0.0 0.0 ± 0.0 0.1 ± 0.0 0.0 ± 0.0 0.1 ± 0.0
f 0.3 ± 0.1 0.3 ± 0.1 0.3 ± 0.1 0.3 ± 0.1 1.2 ± 0.2b,d
ALP m 119 ± 5b 150 ± 6d 150 ± 7d 148 ± 6d 155 ± 4d
f 122 ± 6b 158 ± 6d 154 ± 8c 155 ± 9c 164 ± 10d
Albumin m 42 ± 0a 43 ± 0c 43 ± 0b 43 ± 0 44 ± 0b,c
f 46 ± 0 48 ± 0 48 ± 0 48 ± 0a 48 ± 0a
Thrombocyte count (× 109/L) m 794 ± 13 767 ± 20 831 ± 16a 827 ± 15a 876 ± 15b,d
f 844 ± 18 812 ± 19 825 ± 16 828 ± 17 894 ± 23b
PTT (s) m 39.7 ± 0.5b 37.1 ± 0.4d 37.4 ± 0.5d 37.2 ± 0.4d 37.3 ± 0.4d
f 35.4 ± 0.4 34.0 ± 0.3 34.4 ± 0.4 34.1 ± 0.4 34.0 ± 0.6
Total cholesterol m 2.15 ± 0.08c 2.60± 0.06d 2.60 ± 0.10d 2.52 ± 0.05d 2.28 ± 0.08a
(mmol/L) f 1.76 ± 0.05b 2.18 ± 0.07d 2.06 ± 0.05d 2.04 ± 0.06d 2.05 ± 0.05d
HDL m 1.41 ± 0.06b 1.72 ± 0.05d 1.75 ± 0.07d 1.73 ± 0.05d 1.69 ± 0.06d
(mmol/L) f 1.36 ± 0.04b 1.63 ± 0.06d 1.55 ± 0.05c 1.60 ± 0.03d 1.74 ± 0.05d
Non‐HDL m 0.74 ± 0.04 0.87 ± 0.03 0.85 ± 0.06 0.79 ± 0.04 0.59 ± 0.03c,d
(mmol/L) f 0.40 ± 0.03a 0.55 ± 0.04 0.52 ± 0.04c 0.44 ± 0.05a 0.31 ± 0.02b
Triglycerides m 2.36 ± 0.19 2.10 ± 0.20 2.04 ± 020 1.85 ± 0.15 1.25 ± 0.07b,c
(mmol/L) f 1.32 ± 0.16 1.40 ± 0.17 1.37 ± 0.16 1.14 ± 0.12 0.71 ± 0.04a,c

POC: plant sterol oxidation concentrate.

a

p < 0.05 (vs. PSE = plant sterol esters control).

b

p < 0.01 (vs. PSE control).

c

p < 0.05 (vs. SDC = standard diet control).

d

p < 0.01 (vs. SDC diet).