Table 3.

Relaxations to ACh and SNP in thoracic aortas.

	C	C+CNME	DM	DM+Met	DM+CNME
Acetylcholine (ACh)
Emax (%)	90.14 ± 1.37	88.74 ± 2.13	57.82 ± 2.62####	84.06 ± 1.98∗∗∗∗	83.87 ± 1.27∗∗∗∗
Sodium nitroprusside (SNP)
Emax (%)	108.90 ± 4.63	112.40 ± 4.99	124.00 ± 8.30	114.40 ± 4.18	115.40 ± 6.89

Data are presented as mean ± SEM (n = 12). ^####P < 0.0001 vs. C. ^∗∗∗∗P < 0.0001 vs. DM.