Table 1.
BRAF mutations detected by the Idylla BRAF mutation test.
Exon | Codon | Mutation | Nucleotide change | Protein | Genetic call |
---|---|---|---|---|---|
15 | 600 | V600E | p.(Val600Glu) | (c.1799T>A) | V600E/E2/D |
V600E2 | p.(Val600Glu) | (c.1799_1800delinsAA) | |||
V600D | p.(Val600Asp) | (c.1799_1800delinsAT; c.1799_1800delinsAC) | |||
600 | V600K | p.(Val600Lys) | (c.1798 _ 1799delinsAA) | V600K/R/M | |
V600R | p.(Val600Arg) | (c.1798 _ 1799delinsAG) | |||
V600M | p.(Val600Met) | (c.1798G>A) |