TABLE 1.
Key characteristics of the genome sequences of H. pylori reisolates from human volunteers challenged with strain BCS 100a
| Strain | Location | Genome length (bp) |
No. of SNPs |
Mutation rate changes/site/yr |
||
|---|---|---|---|---|---|---|
| Unique | Pair specific | Total | ||||
| H1 | Challenge | 1,563,305 | ||||
| 8A3 | Antrum | 1,563,267 | 1 | 1 | 2 | 6.67E−06 |
| 8C10 | Corpus | 1,563,260 | 1 | 1 | 2 | 6.67E−06 |
| 12A3 | Antrum | 1,563,420 | 1 | 0 | 1 | 3.34E−06 |
| 12C8 | Corpus | 1,563,409 | 1 | 0 | 1 | 3.34E−06 |
| 29A2 | Antrum | 1,563,333 | 1 | 0 | 1 | 3.34E−06 |
| 29C8 | Corpus | 1,561,020 | 2 | 0 | 2 | 6.68E−06 |
| 48A2 | Antrum | 1,563,280 | 0 | 1 | 1 | 3.34E−06 |
| 48C8 | Corpus | 1,563,290 | 0 | 1 | 1 | 3.34E−06 |
| 78A3 | Antrum | 1,563,274 | 2 | 0 | 2 | 6.67E−06 |
| 78C8 | Corpus | 1,563,292 | 0 | 0 | 0 | 0.00E+00 |
| 81A1 | Antrum | 1,563,405 | 1 | 0 | 1 | 3.34E−06 |
| 81C9 | Corpus | 1,563,438 | 0 | 0 | 0 | 0.00E+00 |
| 87A3 | Antrum | 1,563,302 | 3 | 0 | 3 | 1.00E−05 |
| 87C7 | Corpus | 1,563,411 | 0 | 0 | 0 | 0.00E+00 |
| 103A4 | Antrum | 1,563,266 | 1 | 0 | 1 | 3.34E−06 |
| 103C8 | Corpus | 1,566,721 | 3 | 0 | 3 | 9.98E−06 |
| 125A2 | Antrum | 1,563,276 | 1 | 0 | 1 | 3.34E−06 |
| 125C7 | Corpus | 1,563,239 | 2 | 0 | 2 | 6.67E−06 |
| 119A2 | Antrum | 1,563,232 | 2 | 0 | 2 | 6.67E−06 |
| 119C10 | Corpus | 1,563,317 | 1 | 0 | 1 | 3.34E−06 |
| Total | 23 | 2 | 25 | 4.50E−06 | ||
a
The letters A and C in the reisolate names indicates whether a strain was cultured from antrum (A) or corpus (C) biopsy specimens.