Table 1 ∣.
Feature | Lamivudine & adefovir (n = 22) |
Adefovir (n = 19) |
---|---|---|
Age (years)* | 46 (14) | 45 (13) |
Gender, male | 16 (73%) | 18 (95%) |
Race | ||
White | 9 (41%) | 8 (42%) |
Asian | 9 (41%) | 10 (53%) |
Black | 4 (18%) | 1 (5%) |
Treatment-naïve | 17 (77%) | 14 (74%) |
Genotype | ||
A | 11 (50%) | 7 (37%) |
B | 5 (23%) | 3 (16%) |
C | 2 (9%) | 7 (37%) |
D | 2 (9%) | 2 (10%) |
A/G | 2 (9%) | 0 (0%) |
ALT (U/L)* | 183 (250) | 87 (56) |
HBeAg-positive | 17 (77%) | 14 (74%) |
HBV DNA (Log10 Copies/mL)* | 8.1 (1.3) | 7.8 (1.6) |
Liver histology | ||
Total HAI* | 8.1 (2.7) | 7.9 (2.4) |
Ishak Fibrosis Score* | 3.3 (1.7) | 2.4 (1.5) |
Cirrhosis (%) | 5 (23) | 2 (11) |
HAI, histology activity index.
Mean (s.d.).