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. 2020 Jul 20;44(4):1365–1374. doi: 10.3892/or.2020.7697

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Copyright: © Gao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Xanth inhibits the growth of non-small cell lung cancer cells in vitro. (A) Chemical structure of Xanth. (B) Analysis of the toxicity of Xanth on immortalized lung epithelial cell lines HBE and NL20. HBE and NL20 cells were treated with Xanth for 72 h. Cell viability was analyzed by the MTS assay. (C) MTS analysis of the inhibitory effect of Xanth on HCC827 (left), H1975 (middle) and H23 (right) cells. (D) A soft agar assay was performed to assess the inhibitory effect of Xanth on HCC827 (top), H1975 (middle) and H23 (bottom) cells (scale bar, 200 µm). *P<0.05, **P<0.01, ***P<0.001. Xanth, xanthohumol.