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. 2020 Aug 3;44(4):1393–1402. doi: 10.3892/or.2020.7713

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Curcumin induced apoptosis of PANC-1 cells and enhanced the pro-apoptotic effects of gemcitabine or docetaxel on PANC-1 cells. (A) TEM was conducted to observe morphological changes of apoptosis and necrosis in the indicated groups. (B) Apoptotic morphological changes including nuclear fragmentation and condensation were observed in DAPI staining experiments. Red arrows: Typical nuclear changes of apoptotic cells. (C) Statistical analysis of apoptosis percentage on PANC-1 cells under different drug combinations (*P<0.05 and **P<0.01). 10C: 10 µM curcumin, 20C: 20 µM curcumin.