Table 3.

Plasma total estrogen and testosterone (TES) of Int-control, CsX, CsX-TRT, CsX-LST, and CsX-LST-TRT male SD rats

Group	Total estrogen (pg mL−1)	Testosterone (TES) (ng mL−1)
InT-control	30.7 ± 0.6	0.72 ± 0.2
CsX	30.9 ± 1.2	---- a
CsX-TRT	31.3 ± 0.5	0.96 ± 0.1
CsX-LST	32.7 ± 0.2	---- a
CsX-LST-TRT	33.2 ± 0.6	1.14 ± 0.1

Male Sprague-Dawley (SD) rats: intact (InT-control), bilaterally castrated (CsX), and CsX with TES therapy (CsX-TRT; 1.75 mg kg⁻¹; sc, 2x/week). In a separate experiment, CsX males were given drinking water with losartan (250 mg L⁻¹) without TES therapy (CsX-LST) or with TES therapy (CsX-LST-TRT; 1.75 mg kg⁻¹; sc, 2x/week). Data are means ± SEM (n = 6-13 rats per group). Neither total estrogen nor TES concentrations differed significantly among the five experimental groups (P > 0.05)

^aPlasma TES levels in CsX and CsX-LST groups were below the detectable limits of the radioimmunoassay