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. 2020 Jul 17;44(4):1375–1384. doi: 10.3892/or.2020.7694

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Copyright: © Wen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 6. — Knockdown of MCM3AP-AS1 inhibits OC tumor growth in vivo. (A) Tumor volumes were measured every 7 day until the mice were sacrificed. (B) Tumor images was captured at the end of the experiments. (C) Tumor weight was measured at the end of the experiments. (D) Ki-67 expression was determined in xenograft tumors by IHC. (E) Relative expression of MCM3AP-AS1, miR-143-3p and TAK1 was determined in xenograft tumors by RT-qPCR. All experiments were performed in triplicate and are expressed as mean ± SD. *P<0.05, **P<0.01, ***P<0.001. MCM3AP-AS1, MCM3AP antisense 1; OC, ovarian cancer; TAK1, transforming growth factor-β-activated kinase 1.