Table 2.
Region of Interest | ||||||
---|---|---|---|---|---|---|
Left Amygdala | Right Amygdala | Left + Right Amygdala | ||||
Region of Interest Definition | Correlation Coefficient (r) | p Value | Correlation Coefficient (r) | p Value | Correlation Coefficient (r) | p Value |
Anatomical (FreeSurfer Segmentation) | −.41 | .03 | −.28 | .16 | −.36 | .06 |
Functional (Voxel Threshold .05) | −.52 | .01 | −.42 | .03 | −.50 | .01 |
Functional (Voxel Threshold .01) | −.52 | .01 | −.36 | .06 | −.46 | .01 |
Functional (Voxel Threshold .001) | −.49 | .01 | −.35 | .07 | −.45 | .02 |
Amygdala responses for each subject were extracted using regions of interest that were either defined anatomically (in the primary analysis) or defined using the between-group comparison (family history of depression vs. no family history of depression) voxelwise maps generated using 3 different thresholds (p = .05, p = .01, and p = .001). Significant correlations with resilience levels (measured using the Connor-Davidson Resilience Scale) in the family history–positive group [n = 27]) are observed regardless of the type of amygdala region of interest used to extract the functional magnetic resonance imaging data.