TABLE 2.

Azithromycin negatively impacts diagnostic positivity (phage excluded)

Dxg	Na	Dx positive [% (no. positive/total no.)] by phage exposure:		ORb	OR_MLEc	CIc	P valued
		Exposed	Unexposed
RDT	63	0 (0/18)	49 (22/45)	0.000	0.000	0.000–0.282	<0.001
qPCR	63	33 (6/18)	82 (37/45)	0.108	0.113	0.026–0.437	<0.001
Microscopye	58	44 (7/16)	60 (25/42)	0.529	0.535	0.139–1.973	0.378
Culturef	27	0 (0/5)	59 (13/22)	0.000	0.000	0.000–0.997	0.041

^aNumber of V. cholerae-positive samples by nl-qPCR without lytic bacteriophage (ICP1, ICP2, and ICP3) detected in the stool by PCR.

^bOR, sample odds ratio.

^cEstimated odds ratio with conditional maximum likelihood estimate (MLE); CI, 95% confidence interval.

^dFisher's exact test.

^eIndeterminant samples were considered negative; limit of detection 100 to 1,000 CFU/ml.

^fInsufficient samples with phage for statistical analysis.

^gDx, diagnostic.